With .NET 4.5 Micorsoft gave developers a new tool to solve the problem: portable libraries! There is a new project template called Portable Class Library. If you select it, a dialog box appears asking you which platforms should be targeted:
The selected settings can later be changed using the project properties. The class library can be directly referenced in a Silverlight project as well as in WPF, which was not possible before: an assembly targeted to the .NET Framework could not be referenced from Silverlight.
Some drawbacks...
As every nice feature, this has its drawbacks as well. Of course in the PCL project you can only use a subset of all supported plattforms. On MSDN is a list of supported features. A PCL project can not reference platform specific assemblies - it is limited to other PCL assemblies.A major thing I miss in contrast to the old school multiple DLL with shared files approach is, that you can no longer use compiler directives to use platform specific code. Neither can you effectivly determine on what platform your code is running. On the one hand that is the idea of PCL, on the other hand it seems like a limitiation to me.